职称:教授
称号:山东省优青
研究方向:功能性高分子及纳米材料在生物医药中的应用
主持科研项目(按时间倒序):
1、山东省自然科学基金面上项目,超氧化物歧化纳米酶的制备及其防治肿瘤光热治疗副作用的研究(ZR2018MEM016),2018/03-2021/06,18万元,在研。
2、山东省优秀青年基金项目,氧化还原纳米酶的制备及其绿色催化合成水溶性导电聚合物肿瘤光热治疗剂的研究(ZR2015JL017),2015/06-2017/12,30万元,已结题。
3、山东省优秀中青年科研奖励基金项目,磷酸盐纳米颗粒过氧化氢模拟酶的制备及其生物催化活性的研究(BS2012CL015),2012/07-2014/01,6万元,已结题。
4、青岛市科技发展计划项目磷酸盐纳米颗粒氧化还原模拟酶的制备及其生物催化机理研究(13-1-4-182-jch),2013/01-2015/12,5万元,在研。
5、国家青年自然科学基金项目,硼酸生物自润滑材料的合成与生物摩擦学研究(5090207),2010/01-2012/12,20万元,已结题。
6、青岛市科技发展计划项目,人工关节软骨纳米润滑材料的研究(10-3-4-4-13-jch),2010/01-2012/09,5万元,已结题。
主要论著(按时间倒序)
1. Zhongqiang Wang, Guoliang Li, Yang Gao, Ying Yu, Bing Li, Xingkai Wang, Jinjian Liu, Kezheng Chen, Jianfeng Liu, Wei Wang, Trienzyme-like Iron Phosphates-Based (FePOs) Nanozyme for Enhanced Anti-tumor Efficiency with Minimal Side Effects, Chemical Engineering Journal, 2021, 404: 125574(通讯作者)
2. Guoliang Li, Weihua Wang, Shaoxin Song, Yajun Sun, Jianfeng Liu, Kezheng Chen, Jinjian Liu, Wei Wang, Anti-cancer Effect and Cell Death Pathways in Ultralow Power 980 nm Laser Triggered Photodynamic Therapy by Gd2O3:Yb,Tm Nanoparticles, Journal of Biomedical Nanotechnology, 2019, 15 (3): 462-476(通讯作者)
3. Yajun Sun, Weihua Wang, Weikang Wang, Nailin Yang, Wei Wang, Kezheng Chen, Cell Death Pathway Investigations on Gd2O3:Yb,Tm-MC540 Mediated Photodynamic Therapy of HeLa Cells. Nanomedicine: Nanotechnology, Biology, and Medicine, 2018, 14(5): 1743-1744(通讯作者)
4. Zhentao Hua, Bing Li, Yajun Sun, Kezheng Chen, Wei Wang. Green Synthesis of Water Soluble PEDOT Catalyzed by Copper Phosphate Nanozyme and Cell Death Modes in PEDOT Mediated Photothermal Therapy. Nanomedicine: Nanotechnology, Biology, and Medicine, 2018, 14(5): 1774-1775(通讯作者)
5. Kaixuan Liang, Yajun Sun, Kezheng Chen, Wei Wang. Fluorescent detection of Fe3+ ions in living cells by novel NaTb(SO4)2•H2O nanospheres. Nanomedicine: Nanotechnology, Biology, and Medicine, 2018, 15, 1788-1789(通讯作者)
6. Lijun Yang, Yang Gao, Jinjian Liu, Yumin Zhang, Chunhua Ren, Jing Wang, Zhongqiang Wang, Jianfeng Liu, Liping Chu, Wei Wang, Fan Huang. Silver-Coated Nanoparticles Combined with Doxorubicin for Enhanced Anticancer Therapy, Journal of Biomedical Nanotechnology, 2018, 14 (2): 312-320(通讯作者)
7. Zhentao Hua, Bing Li, Leilei Li, Xiaoyu Yin, Kezheng Chen, Wei Wang. Designing a Novel Photothermal Material of Hierarchical Microstructured Copper Phosphate for Solar Evaporation Enhancement, The Journal of Physical Chemistry C, 2017, 121, 60-69(通讯作者)
8. Wei Wang, Leilei Li, Hao Li, Kaixuan Liang, Kezheng Chen. Nanoscaled red elemental Se peroxidase mimic designed for tumor cell inhibition and green synthesis of water-soluble polyaniline as photothermal therapy agent,Nanomedicine: Nanotechnology, Biology, and Medicine, 2016, 12: 528-529(通讯作者)
9. Leilei Li, Kaixuan Liang, Zhentao Hua, Min Zou, Kezheng Chen and Wei Wang, A green route to water-soluble polyaniline for photothermal therapy catalyzed by iron phosphate peroxidase mimic, Polymer Chemistry-UK, 2015, 6 (12): 2290-2296(通讯作者)
10. Hao Li, Shaoxin Song, Wei Wang and Kezheng Chen. In vitro photodynamic therapy based on magnetic-luminescent Gd2O3:Yb,Er nanoparticles with bright three-photon up-conversion fluorescence under near-infrared light, Dalton Transactions, 2015, 44, 16081-16090(通讯作者)
11. Lei lei Li, Wei Wang and Kezheng Chen, Synthesis of Black Elemental Selenium Peroxidase Mimic and Its Application in Green Synthesis of Water-Soluble Polypyrrole as a Photothermal Agent, The Journal of Physical Chemistry C, 2014, 118(45), 26351-26358(通讯作者)
12. Wei Wang, Dong Xu, Xiaojun Wei, Kezheng Chen. Magnetic-luminescent YbPO4:Er,Dy Microspheres Designed for Tumor Theranostics with Synergistic Effect of Photodynamic, International Journal of Nanomedicine, 2014, 9, 4879-4891(通讯作者)
13. Wei Wang, Xiangpeng Jiang, Kezheng Chen. Iron Phosphate Microflowers as Peroxidase Mimic and Superoxide Dismutase Mimic for Biocatalysis and Biosensing, Chemical Communications, 2012, 48(58): 7289-7291(通讯作者)
14. Wei Wang, Xiangpeng Jiang, Kezheng Chen. CePO4:Tb,Gd Hollow Nanospheres as Peroxidase Mimic and Magnetic-Fluorescent Imaging Agent, Chemical Communications, 2012, 48(54): 6839-6841(通讯作者)
15. Wei Wang, Xiangpeng Jiang, Kezheng Chen. Lanthanide-doped Chitosan nanospheres as Cell Nuclei Illuminator and Fluorescent Nonviral Vector for Plasmid DNA Delivery, Dalton Transactions, 2012, 113(7): 2699-2703(通讯作者)
16. Wei Wang, Min Zou, Kezheng Chen, Novel Fe3O4@YPO4:Re (Re=Tb, Eu) Multifunctional Magnetic-Fluorescent Hybrid Spheres for Biomedical Applications, Chemical Communications, 2010, 41(28): 5100-5102(通讯作者)
17. Wei Wang, Kezheng Chen, Zhikun Zhang. From Borax to Ultralong One-Dimensional Boric Acid, The Journal of Physical Chemistry C, 2009, 113(7): 2699-2703.
已授权专利
1. 王玮,李雷雷,陈克正. 一种纳米黑硒过氧化物模拟酶及其制备方法(授权号ZL 201410559673.0)
2. 王玮,李雷雷,陈克正. 一种纳米黑硒过氧化物模拟酶催化合成水溶性导电聚合物的方法(授权号ZL 201410559724.X)
3.王玮,许冬,陈克正. 一种用作光动力药物载体的上转换荧光微米颗粒的制备方法(授权号ZL 201410558235.2)
4. 王玮,华振涛,李炳,闻益智. 一种磷酸铜纳米球及其制备方法和应用(授权号ZL 201611082104.7)(授权时间2018.4.3)
5. 王玮,梁凯旋,陈克正. 一种硫酸钆钠的制备方法及应用(授权号ZL 201611115217.2)
6. 李炳,王玮,华振涛. 一种磷酸铜微米花球及其制备方法(授权号ZL 201611081227.9)(授权时间2018.8.31)
7. 梁凯旋,宋韶欣,王玮,陈克正. 一种三价铁离子检测试剂及其制备方法和应用(授权号ZL 201710405075.1)
学术会议
1. 口头报告,中国微米纳米技术学会纳米科学技术分会第二届年会暨2010’全国纳米生物与医学学术会议,2010年11月,武汉
2. 口头报告,第九届世界生物材料大会,2012年6月,成都
3. 口头报告,全国生物材料大会,2019年8月,大连
4. 墙报展示,第一届国际纳米药物大会ChinaNanomedicine 2015,2015年4月,杭州
5. 墙报展示,第二届国际纳米药物大会ChinaNanomedicine 2016,2016年10月,武汉
6. 墙报展示,第三届国际纳米药物大会ChinaNanomedicine 2018,2018年10月,上海
7. 墙报展示,5th Symposium on Innovative Polymers for Controlled Delivery (Innovative Delivery),2018年9月,苏州
获奖
1. 2015年,第十四届“挑战杯”山东省大学生课外学术科技作品竞赛“优秀指导教师”,指导作品荣获山东省特等奖、国家三等奖
2. 2017年,指导学生参加第十五届“挑战杯”山东省大学生课外学术科技作品竞赛,并荣获山东省二等奖
3. 2018年,指导学生参加“创青春”山东省大学生创业大赛,并荣获山东省银奖
4. 指导学生获批国家级大学生创新训练计划项目三项